TCT-793 Metformin Impairs Endothelialization After Placement of Newer Generation Drug Eluting Stents
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چکیده
منابع مشابه
Are Newer-Generation Drug-Eluting Stents More Effective in Women than Early-Generation Ones?
Evidence-based research is increasingly aimed at differentiating between no proof of difference (failed demonstration of superiority) and proof of no difference (demonstration of equivalence). The latter requires that equivalence margins are incorporated in the analysis of outcomes. We applied an analysis of equivalence to study the incremental benefit of newer-generation vs earlygeneration dru...
متن کاملStent thrombosis in early-generation drug-eluting stents versus newer-generation everolimus-eluting stent assorted by LVEF.
OBJECTIVE Everolimus drug-eluting stents (EES) are superior to early-generation drug-eluting stents (DES), releasing sirolimus (SES) or paclitaxel (PES) in preventing stent thrombosis (ST). Since an impaired LVEF seems to increase the risk of ST, we aimed to investigate the difference in outcome of patients with varying LVEF using EES versus early-generation DES. METHODS In a prospective coho...
متن کاملStent thrombosis: no longer an issue with newer-generation drug-eluting stents?
Drug-eluting stents (DES) were introduced to address the major limitation of bare metal stents (BMS), namely exuberant neointimal hyperplasia leading to clinical restenosis, which occurred in up to 30% of patients. Sirolimuseluting stents (SES) and paclitaxel-eluting stents (PES)— referred to as early generation DES—by means of controlled release of antiproliferative drugs had a major impact on...
متن کاملDrug-eluting stents: the next generation
The small but absolute increase in late and very late stent thrombosis associated with drug-eluting stent technology may in part be related to the permanent, durable polymers currently employed with these stent platforms. Research has recently focused on two strategies to combat this problem; bioabsorbable polymers and polymer-free stents. This article critically reviews the key clinical trials...
متن کاملThrombosis after implantation of drug-eluting stents.
S tent thrombosis is the sudden occlusion of a stented coronary artery due to thrombus formation. Despite major improvements in antiplatelet therapy, thrombotic events remain the primary cause of death after percutaneous coronary interventions. The clinical consequences of stent thrombosis are frequently catastrophic and include death in 20% to 48% of cases or major myocardial infarction in 60%...
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ژورنال
عنوان ژورنال: Journal of the American College of Cardiology
سال: 2013
ISSN: 0735-1097
DOI: 10.1016/j.jacc.2013.08.1546